Infection Control in U.S. Dental Practice: Current Standards, Guidelines, and Emerging Challenges

Dr. Latifa Elbanna¹, Dr. Sri Valli Durga Bala Vinuthna Darisipudi^2, , Dr. Deepthi Dandu³, Dr. Sree Rekha Movva⁴, Dr. Sameera A Khan⁵, Dr. Anam fazal⁶ and Dr. Sandeep Singh⁷

¹(PhD, Prosthodontics) Faculty of Dental Medicine - AlAzhar University, Cairo, Egypt

²BDS, GDC, Vijayawada, Andhra Pradesh, India

³BDS, Sharavathi Dental College and Hospital, Shimoga. (Rajiv Gandhi University of Health Sciences) India

⁴BDS, Kamineni Institute of Dental Sciences. Sreepuram, Akkinepallivari Lingotam, Telangana, India

⁵BDS, People’s College of Dental Science, Ayodhya Bypass Rd, Bhopal, Madhya Pradesh, India

⁶BDS, CMH Lahore Medical College, institute of Dentistry, Pakistan

⁷MDS (Prosthodontics), Post Graduate Institute of Dental Sciences, Rohtak, India

Cite this paper:
Dr. Latifa Elbanna, Dr. Sri Valli Durga Bala Vinuthna Darisipudi, Dr. Deepthi Dandu, Dr. Sree Rekha Movva, Dr. Sameera A Khan, Dr. Anam fazal and Dr. Sandeep Singh. Infection Control in U.S. Dental Practice: Current Standards, Guidelines, and Emerging Challenges. American Journal of Medical Case Reports. 2026; 14(3):34-41. doi: 10.12691/ajmcr-14-3-1

Abstract

Infection control is a critical component of dental practice, essential for preventing the transmission of infectious agents among patients, dental health care personnel, and the clinical environment. Dental settings pose unique infection risks due to frequent exposure to blood and saliva, use of sharp instruments, and the generation of aerosols during routine procedures. In the United States, infection control in dentistry is guided by evidence-based recommendations from the Centers for Disease Control and Prevention, the Occupational Safety and Health Administration, and professional organizations such as the American Dental Association. This narrative review summarizes current infection control standards and guidelines relevant to U.S. dental practice, including standard precautions, instrument processing and sterilization, environmental infection control, dental unit waterline management, aerosol and airborne infection control measures, and occupational health considerations. The review also highlights emerging challenges, such as evolving infectious threats, antimicrobial resistance, inconsistencies in guideline implementation, resource and cost constraints, and the lasting impact of the COVID-19 pandemic on dental infection control practices. Strengthening infection prevention efforts through continued education, consistent adherence to established guidelines, and adaptability to emerging risks is essential for maintaining patient and provider safety and ensuring high-quality dental care in the United States.

Keywords:
Infection Control Dental Care Cross Infection United States

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References:

[1]	Cleveland JL, Gray SK, Harte JA, Robison VA, Moorman AC, Gooch BF. Transmission of blood-borne pathogens in US dental health care settings: 2016 update. J Am Dent Assoc. 2016; 147(9): 729–738.
[2]	Brian Z, Weintraub JA. Oral health and COVID-19: increasing the need for prevention and access. Prev Chronic Dis. 2020; 17: 200266.
[3]	Kopitnik NL, Kahwaji CI. Universal precautions. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025.
[4]	Centers for Disease Control and Prevention. Recommended infection-control practices for dentistry, 1993. MMWR Recomm Rep. 1993; 42(RR-8): 1–12.
[5]	Patel M. Infection control in dentistry during COVID-19 pandemic: what has changed? Heliyon. 2020; 6(10): e05402.
[6]	Ovretveit J, Mittman BS, Rubenstein LV, Ganz DA. Combining improvement and implementation sciences and practices for the post COVID-19 era. J Gen Intern Med. 2021; 36(11): 3503–3510.
[7]	Kohn WG, Collins AS, Cleveland JL, Harte JA, Eklund KJ, Malvitz DM; Centers for Disease Control and Prevention. Guidelines for infection control in dental health-care settings—2003. MMWR Recomm Rep. 2003; 52(RR-17): 1–61.
[8]	Centers for Disease Control and Prevention. Guidance for dental settings during the COVID-19 response. MMWR. 2020.
[9]	Occupational Safety and Health Administration. Bloodborne pathogens standard (29 CFR 1910.1030).
[10]	Leas BF, Sullivan N, Han JH, et al. Environmental cleaning for the prevention of healthcare-associated infections. AHRQ Technical Briefs. 2015; (22).
[11]	Infection prevention and control in dental practice. Int Dent J. 2022; 72(1): 16–18.
[12]	Bromberg N, Brizuela M. Preventing cross infection in the dental office. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025.
[13]	Markkanen P, Galligan C, Laramie A, Fisher J, Sama S, Quinn M. Understanding sharps injuries in home healthcare. BMC Public Health. 2015; 15: 359.
[14]	Patiño-Marín N, Villa García LD, Aguirre López EC, et al. Sterilization and disinfection: ensuring infection control in dental practices. Cureus. 2025; 17(2): e79041.
[15]	Vatanparast B, Buitrago JM, Siqueira MF. Exploring sterilizer performance through external biological indicator testing. BMC Oral Health. 2024; 24(1): 1361.
[16]	Sakchhi S, Elbanna L, Chakor M, et al. Green dentistry: sustainable practices and materials for a healthier planet. Int J Dent Mater. 2025; 7(3): 84–92. 3
[17]	Van der Weijden F. Aerosol in the oral health-care setting: a misty topic. Clin Oral Investig. 2023; 27(Suppl 1):23–32.
[18]	Harrel SK, Molinari J. Aerosols and splatter in dentistry: a brief review of the literature and infection control implications. J Am Dent Assoc. 2004; 135(4): 429–437.
[19]	Ghoneim A, Proaño D, Kaur H, Singhal S. Aerosol-generating procedures and associated control measures. Can J Dent Hyg. 2024; 58(1): 48–63.
[20]	Alharbi G, Shono N, Alballaa L, Aloufi A. Knowledge, attitude and compliance of infection control guidelines among dental faculty members and students. BMC Oral Health. 2019; 19(1):7.
[21]	Peng X, Xu X, Li Y, Cheng L, Zhou X, Ren B. Transmission routes of 2019-nCoV and controls in dental practice. Int J Oral Sci. 2020; 12(1): 9.
[22]	Tang KWK, Millar BC, Moore JE. Antimicrobial resistance. Br J Biomed Sci. 2023; 80: 11387.
[23]	Yamalik N, Nemli SK, Carrilho E, et al. Implementation of evidence-based dentistry into practice. Int Dent J. 2015; 65(3): 127–145.
[24]	Tysiąc-Miśta M, Dubiel A, Brzoza K, et al. Air disinfection procedures in the dental office during the COVID-19 pandemic. Med Pr. 2021; 72(1): 39–48.
[25]	Hong F, Chen P, Yu X, Chen Q. Application of silver to decontaminate dental unit waterlines. Biol Trace Elem Res. 2022; 200(12): 4988–5002.
[26]	Mahasneh AM, Alakhras M, Khabour OF, et al. Practices of infection control among dental care providers. Clin Cosmet Investig Dent. 2020; 12: 281–289.
[27]	Upendran A, Gupta R, Geiger Z. Dental infection control. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025.
[28]	Gracco A, De Stefani A, Bruno G. Influence of new technology in dental care: a public health perspective. Int J Environ Res Public Health. 2023; 20(7): 5364.
[29]	Volgenant CMC, Persoon IF, de Ruijter RAG, de Soet JJH. Infection control in dental health care during and after SARS-CoV-2. Oral Dis. 2021; 27(Suppl 3): 674–683.
[30]	Saikiran KV, Sahiti PS, Mounika SVM, et al. Evidence-based management guidelines in dentistry during COVID-19. Med Pharm Rep. 2021; 94(4): 417–424.
[31]	Sangani K, Gill AK, Chakor M, et al. Teledentistry: a comprehensive review. Sch J Dent Sci. 2025; 12(5): 74–80.
[32]	Nunes MC, Thommes E, Fröhlich H, et al. Redefining pandemic preparedness. Infect Dis Model. 2024; 9(2): 501–518.
[33]	AlSaiari AK, Alonazi MS, Alotaibi NM, et al. Bioengineering innovations in global dental infection control. Int Dent J. 2025; 75(3): 2222–2238.
[34]	Zia H, Singh R, Seth M, Ahmed A, Azim A. Engineering solutions for preventing airborne transmission. Indian J Crit Care Med. 2021; 25(4): 453–460.
[35]	Havill NL. Best practices in disinfection of noncritical surfaces. Am J Infect Control. 2013; 41(5 Suppl): S26–S30.
[36]	Isha SN, Ahmad A, Kabir R, Apu EH. Dental clinic architecture prevents COVID-19-like infectious diseases. HERD. 2020; 13(4): 240–241.
[37]	Valentino AL, Juanico JF. Overcoming barriers to applied research. Behav Anal Pract. 2020; 13(4): 894–904.
[38]	Rachael E. Infection prevention and control in dental practice. Int Dent J. 2020; 70(1): 17–18.
[39]	Peter D, Meng M, Kugler C, Mattner F. Strategies to promote infection prevention and control. Am J Infect Control. 2018; 46(2): 207–216.
[40]	Myers R, Larson E, Cheng B, et al. Hand hygiene among general practice dentists. J Am Dent Assoc. 2008; 139(7): 948–957.
[41]	Ibrahim NK, Alwafi HA, Sangoof SO, et al. Cross-infection and infection control in dentistry. J Infect Public Health. 2017; 10(4): 438–445.
[42]	Rutala WA, Weber DJ. Disinfectants used for environmental disinfection. Am J Infect Control. 2013; 41(5 Suppl): S36–S41.